This module discusses the practical aspects of platelet morphological features and its role in routine hematology practice. It explains how variations in platelet size, granularity, and number can provide valuable diagnostic clues. The session focuses on common laboratory challenges (including platelet clumping, giant platelets, gray platelets, and microplatelets) and explains how these findings can lead to inaccurate automated platelet counts if not recognized during blood film reviews. The discussion also highlights the importance of correlating platelet morphological features with other blood film findings to identify inherited platelet disorders, reactive conditions, hematologic malignancies, thrombotic microangiopathies, and infectious diseases, such as malaria. Throughout the discussion, emphasis is placed on the role of laboratory professionals in verifying automated analyzer results, performing manual platelet estimation when required, and ensuring clinically meaningful reporting to support accurate diagnosis and patient management.